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1,25-Dihydroxyvitamin D Deficiency Accelerates Aging-related Osteoarthritis via Downregulation of Sirt1 in Mice

Emerging observational data suggest that vitamin D deficiency is associated with the onset and progression of knee osteoarthritis (OA). However, the relationship between vitamin D level and OA and the role of vitamin D supplementation in the prevention of knee OA are controversial. To address these...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Zhang, Jiao, Li, Jie, Qin, Ran, Lu, Na, Goltzman, David, Miao, Dengshun, Yang, Renlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830508/
https://www.ncbi.nlm.nih.gov/pubmed/36632467
http://dx.doi.org/10.7150/ijbs.78785