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1,25-Dihydroxyvitamin D Deficiency Accelerates Aging-related Osteoarthritis via Downregulation of Sirt1 in Mice
Emerging observational data suggest that vitamin D deficiency is associated with the onset and progression of knee osteoarthritis (OA). However, the relationship between vitamin D level and OA and the role of vitamin D supplementation in the prevention of knee OA are controversial. To address these...
Autores principales: | Chen, Jie, Zhang, Jiao, Li, Jie, Qin, Ran, Lu, Na, Goltzman, David, Miao, Dengshun, Yang, Renlei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830508/ https://www.ncbi.nlm.nih.gov/pubmed/36632467 http://dx.doi.org/10.7150/ijbs.78785 |
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