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Apelin promotes osteosarcoma metastasis by upregulating PLOD2 expression via the Hippo signaling pathway and hsa_circ_0000004/miR-1303 axis

Osteosarcoma is a highly mortal bone tumor, with a high metastatic potential, promoted in part by the enzyme procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 (PLOD2). Increasing level of PLOD2 in osteosarcoma tissue correlates with lymphatic and distant metastasis. The adipokine apelin (APLN) is al...

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Detalles Bibliográficos
Autores principales: Trang, Nguyen Thi Nha, Lai, Chao-Yang, Tsai, Hsiao-Chi, Huang, Yuan-Li, Liu, Shan-Chi, Tsai, Chun-Hao, Fong, Yi-Chin, Tzeng, Huey-En, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830518/
https://www.ncbi.nlm.nih.gov/pubmed/36632453
http://dx.doi.org/10.7150/ijbs.77688