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A computational approach to identify efficient RNA cleaving 10–23 DNAzymes

DNAzymes are short pieces of DNA with catalytic activity, capable of cleaving RNA. DNAzymes have multiple applications as biosensors and in therapeutics. The high specificity and low toxicity of these molecules make them particularly suitable as therapeutics, and clinical trials have shown that they...

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Detalles Bibliográficos
Autores principales: Pine, Angela C, Brooke, Greg N, Marco, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830538/
https://www.ncbi.nlm.nih.gov/pubmed/36632612
http://dx.doi.org/10.1093/nargab/lqac098