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Sleep slow-wave oscillations trigger seizures in a genetic epilepsy model of Dravet syndrome

Sleep is the preferential period when epileptic spike–wave discharges appear in human epileptic patients, including genetic epileptic seizures such as Dravet syndrome with multiple mutations including SCN1A mutation and GABA(A) receptor γ2 subunit Gabrg2(Q390X) mutation in patients, which presents m...

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Detalles Bibliográficos
Autores principales: Catron, Mackenzie A, Howe, Rachel K, Besing, Gai-Linn K, St. John, Emily K, Potesta, Cobie Victoria, Gallagher, Martin J, Macdonald, Robert L, Zhou, Chengwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830548/
https://www.ncbi.nlm.nih.gov/pubmed/36632186
http://dx.doi.org/10.1093/braincomms/fcac332