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SARS-CoV-2 viral entry and replication is impaired in Cystic Fibrosis airways due to ACE2 downregulation

As an inherited disorder characterized by severe pulmonary disease, cystic fibrosis could be considered a comorbidity for coronavirus disease 2019. Instead, current clinical evidence seems to be heading in the opposite direction. To clarify whether host factors expressed by the Cystic Fibrosis epith...

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Detalles Bibliográficos
Autores principales: Bezzerri, Valentino, Gentili, Valentina, Api, Martina, Finotti, Alessia, Papi, Chiara, Tamanini, Anna, Boni, Christian, Baldisseri, Elena, Olioso, Debora, Duca, Martina, Tedesco, Erika, Leo, Sara, Borgatti, Monica, Volpi, Sonia, Pinton, Paolo, Cabrini, Giulio, Gambari, Roberto, Blasi, Francesco, Lippi, Giuseppe, Rimessi, Alessandro, Rizzo, Roberta, Cipolli, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830623/
https://www.ncbi.nlm.nih.gov/pubmed/36627352
http://dx.doi.org/10.1038/s41467-023-35862-0