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Glycosylation Profiling of the Neoplastic Biomarker Alpha Fetoprotein through Intact Mass Protein Analysis

[Image: see text] Elevated serum alpha-fetoprotein (AFP) can be observed in liver cirrhosis and hepatocellular carcinoma (HCC). The glycosylation patterns of AFP have been shown to differentiate these conditions, with AFP glycoforms with core fucosylation (AFP-L3) serving as a malignancy risk predic...

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Detalles Bibliográficos
Autores principales: Dunbar, Carmen, Kushnir, Mark M., Yang, Yifei K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830635/
https://www.ncbi.nlm.nih.gov/pubmed/36541409
http://dx.doi.org/10.1021/acs.jproteome.2c00656