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Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation

[Image: see text] The development of metastasis severely reduces the life expectancy of patients with colorectal cancer (CRC). Although loss of SMAD4 is a key event in CRC progression, the resulting changes in biological processes in advanced disease and metastasis are not fully understood. Here, we...

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Detalles Bibliográficos
Autores principales: Dijkstra, Jelmer J., Neikes, Hannah K., Rezaeifard, Somayeh, Ma, Xuhui, Voest, Emile E., Tauriello, Daniele V. F., Vermeulen, Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830641/
https://www.ncbi.nlm.nih.gov/pubmed/36450103
http://dx.doi.org/10.1021/acs.jproteome.2c00551