Room-temperature structural studies of SARS-CoV-2 protein NendoU with an X-ray free-electron laser

NendoU from SARS-CoV-2 is responsible for the virus’s ability to evade the innate immune system by cleaving the polyuridine leader sequence of antisense viral RNA. Here we report the room-temperature structure of NendoU, solved by serial femtosecond crystallography at an X-ray free-electron laser to...

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Detalles Bibliográficos
Autores principales: Jernigan, Rebecca J., Logeswaran, Dhenugen, Doppler, Diandra, Nagaratnam, Nirupa, Sonker, Mukul, Yang, Jay-How, Ketawala, Gihan, Martin-Garcia, Jose M., Shelby, Megan L., Grant, Thomas D., Mariani, Valerio, Tolstikova, Alexandra, Sheikh, Michelle Z., Yung, Mimi Cho, Coleman, Matthew A., Zaare, Sahba, Kaschner, Emily K., Rabbani, Mohammad Towshif, Nazari, Reza, Zacks, Michele A., Hayes, Brandon, Sierra, Raymond G., Hunter, Mark S., Lisova, Stella, Batyuk, Alexander, Kupitz, Christopher, Boutet, Sebastien, Hansen, Debra T., Kirian, Richard A., Schmidt, Marius, Fromme, Raimund, Frank, Matthias, Ros, Alexandra, Chen, Julian J.-L., Botha, Sabine, Fromme, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830665/
https://www.ncbi.nlm.nih.gov/pubmed/36630960
http://dx.doi.org/10.1016/j.str.2022.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830665/
https://www.ncbi.nlm.nih.gov/pubmed/36630960
http://dx.doi.org/10.1016/j.str.2022.12.009

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