Extracellular Vesicles Expressing CD19 Antigen Improve Expansion and Efficacy of CD19-Targeted CAR-T Cells

BACKGROUND: CAR-T cell therapy is effective in the treatment of certain hematological malignancies, and the expansion and functional persistence of CAR-T cells in vivo are crucial to clinical efficacy. The aim of this study was to investigate the potential of extracellular vesicles (EVs) modified wi...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanyuan, Ge, Tong, Huang, Meijuan, Qin, Yun, Liu, Tianjiao, Mu, Wei, Wang, Gaoxiang, Jiang, Lijun, Li, Tongjuan, Zhao, Lei, Wang, Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830716/
https://www.ncbi.nlm.nih.gov/pubmed/36636644
http://dx.doi.org/10.2147/IJN.S390720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830716/
https://www.ncbi.nlm.nih.gov/pubmed/36636644
http://dx.doi.org/10.2147/IJN.S390720

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