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A retrospective on statistical mechanical models for hemoglobin allostery

Understanding allosteric interactions in proteins has become one of the major research areas in protein science. The original aim of the famous theoretical model of Monod, Wyman, and Changeux (MWC) was to explain the regulation of enzymatic activity in biochemical pathways. However, its first succes...

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Detalles Bibliográficos
Autor principal: Eaton, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830738/
https://www.ncbi.nlm.nih.gov/pubmed/36379793
http://dx.doi.org/10.1063/5.0127585