Alpha-B-Crystallin overexpression is sufficient to promote tumorigenesis and metastasis in mice

BACKGROUND: αB-Crystallin is a heat shock chaperone protein which binds to misfolded proteins to prevent their aggregation. It is overexpressed in a wide-variety of cancers. Previous studies using human cancer cell lines and human xenograft models have suggested potential tumor promoter (oncogene) r...

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Detalles Bibliográficos
Autores principales: Rashidieh, Behnam, Bain, Amanda Louise, Tria, Simon Manuel, Sharma, Sowmya, Stewart, Cameron Allan, Simmons, Jacinta Ley, Apaja, Pirjo M., Duijf, Pascal H. G., Finnie, John, Khanna, Kum Kum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830749/
https://www.ncbi.nlm.nih.gov/pubmed/36624493
http://dx.doi.org/10.1186/s40164-022-00365-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830749/
https://www.ncbi.nlm.nih.gov/pubmed/36624493
http://dx.doi.org/10.1186/s40164-022-00365-z

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