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Valproic acid as adjuvant treatment for convulsive status epilepticus: a randomised clinical trial

BACKGROUND: Generalised convulsive status epilepticus (GCSE) is a medical emergency. Guidelines recommend a stepwise strategy of benzodiazepines followed by a second-line anti-seizure medicine (ASM). However, GCSE is uncontrolled in 20–40% patients and is associated with protracted hospitalisation,...

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Detalles Bibliográficos
Autores principales: Sharshar, Tarek, Porcher, Raphaël, Asfar, Pierre, Grimaldi, Lamiae, Jabot, Julien, Argaud, Laurent, Lebert, Christine, Bollaert, Pierre-Edouard, Harlay, Marie Line, Chillet, Patrick, Maury, Eric, Santoli, Francois, Blanc, Pascal, Sonneville, Romain, Vu, Dinh Chuyen, Rohaut, Benjamin, Mazeraud, Aurelien, Alvarez, Jean-Claude, Navarro, Vincent, Clair, Bernard, Outin, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830759/
https://www.ncbi.nlm.nih.gov/pubmed/36624526
http://dx.doi.org/10.1186/s13054-022-04292-7