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GSDMD-mediated pyroptosis dominantly promotes left ventricular remodeling and dysfunction in post-myocardial infarction: a comparison across modes of programmed cell death and mitochondrial involvement

BACKGROUND: Myocardial infarction (MI) has recently accounted for more than one-third of global mortality. Multiple molecular pathological pathways, such as oxidative stress, inflammation, and mitochondrial dysfunction, have been recognized as possible mechanisms in the development of MI. Furthermor...

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Detalles Bibliográficos
Autores principales: Piamsiri, Chanon, Maneechote, Chayodom, Jinawong, Kewarin, Arunsak, Busarin, Chunchai, Titikorn, Nawara, Wichwara, Chattipakorn, Siriporn C, Chattipakorn, Nipon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830763/
https://www.ncbi.nlm.nih.gov/pubmed/36627703
http://dx.doi.org/10.1186/s12967-023-03873-6