α-NETA down-regulates CMKLR1 mRNA expression in ileum and prevents body weight gains collaborating with ERK inhibitor PD98059 in turn to alleviate hepatic steatosis in HFD-induced obese mice but no impact on ileal mucosal integrity and steatohepatitis progression

BACKGROUND: Studies on chemerin/chemokine-like receptor-1 have mainly focused on adipose and liver with the intestinal tissues largely overlooked. In this study conducted on obese mice, we have explored: 1) CMKLR1 expression in the ileums; 2) CMKLR1 inhibitor α-NETA on body weight and intestinal muc...

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Detalles Bibliográficos
Autores principales: Zheng, Canbin, Zheng, Yongping, Chen, Xi, Zhong, Xianyang, Zheng, Xiaobin, Yang, Shuhui, Zheng, Zihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830776/
https://www.ncbi.nlm.nih.gov/pubmed/36624417
http://dx.doi.org/10.1186/s12902-023-01267-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830776/
https://www.ncbi.nlm.nih.gov/pubmed/36624417
http://dx.doi.org/10.1186/s12902-023-01267-9

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