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Bone marrow mesenchymal stem cell-derived exosomal lncRNA KLF3-AS1 stabilizes Sirt1 protein to improve cerebral ischemia/reperfusion injury via miR-206/USP22 axis

BACKGROUND: Cerebral ischemia/reperfusion (I/R) is a pathological process that occurs in ischemic stroke. Bone marrow mesenchymal stem cell-derived exosomes (BMSC-Exos) have been verified to relieve cerebral I/R-induced inflammatory injury. Hence, we intended to clarify the function of BMSC-Exos-del...

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Detalles Bibliográficos
Autores principales: Xie, Xiaowei, Cao, Yu, Dai, Liangping, Zhou, Dingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830826/
https://www.ncbi.nlm.nih.gov/pubmed/36627572
http://dx.doi.org/10.1186/s10020-022-00595-1