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Screening of major hepatotoxic components of Tripterygium wilfordii based on hepatotoxic injury patterns

BACKGROUND: Tripterygium wilfordii Hook. F. (TwHF), a traditional Chinese medicine, is widely used in the treatment of rheumatoid arthritis. Due to multiorgan toxicity, particularly hepatotoxicity, the application of TwHF is restricted. To clarify the hepatotoxic substances, zebrafish, hepatocytes a...

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Detalles Bibliográficos
Autores principales: Li, Meng, Luo, Qiong, Chen, Xi, Qiu, Furong, Tao, Yanyan, Sun, Xin, Liu, Chenghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830834/
https://www.ncbi.nlm.nih.gov/pubmed/36627617
http://dx.doi.org/10.1186/s12906-023-03836-w