CRHR1 antagonist alleviates LPS-induced depression-like behaviour in mice

BACKGROUND: Maladaptation of the HPA (hypothalamic–pituitary–adrenal) axis plays an important role in depression-like behaviour, but the specific molecular mechanisms are unknown. Here, we determined the roles of CRHR1 (corticotrophin releasing hormone receptor 1) and nectin3 in LPS (lipopolysacchar...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jie, Qiu, Lili, Zhang, Hui, Zhou, Zhiqiang, Ju, Lingsha, Yang, Jiaojiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830857/
https://www.ncbi.nlm.nih.gov/pubmed/36624454
http://dx.doi.org/10.1186/s12888-023-04519-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830857/
https://www.ncbi.nlm.nih.gov/pubmed/36624454
http://dx.doi.org/10.1186/s12888-023-04519-z

Ejemplares similares