Cargando…

CRHR1 antagonist alleviates LPS-induced depression-like behaviour in mice

BACKGROUND: Maladaptation of the HPA (hypothalamic–pituitary–adrenal) axis plays an important role in depression-like behaviour, but the specific molecular mechanisms are unknown. Here, we determined the roles of CRHR1 (corticotrophin releasing hormone receptor 1) and nectin3 in LPS (lipopolysacchar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Jie, Qiu, Lili, Zhang, Hui, Zhou, Zhiqiang, Ju, Lingsha, Yang, Jiaojiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830857/ https://www.ncbi.nlm.nih.gov/pubmed/36624454 http://dx.doi.org/10.1186/s12888-023-04519-z

Ejemplares similares

A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome
por: Cursano, Silvia, et al.
Publicado: (2020)

Immunolocalization of Corticotropin-Releasing Hormone (CRH) and Its Receptors (CRHR1 and CRHR2) in Human Endometrial Carcinoma: CRHR1 as a Potent Prognostic Factor
por: Sato, Naoko, et al.
Publicado: (2014)

Aneurysmal subarachnoid haemorrhage: effect of CRHR1 genotype on fatigue and depression
por: Vetkas, Artur, et al.
Publicado: (2020)

Comorbidity of CRHR2 gene variants in type 2 diabetes and depression
por: Amin, M., et al.
Publicado: (2022)

Differential Expression of CRH, UCN, CRHR1 and CRHR2 in Eutopic and Ectopic Endometrium of Women with Endometriosis
por: Vergetaki, Aikaterini, et al.
Publicado: (2013)

Comorbidity of Novel CRHR2 Gene Variants in Type 2 Diabetes and Depression
por: Amin, Mutaz, et al.
Publicado: (2022)

Novel corticotropin-releasing hormone receptor genes (CRHR1 and CRHR2) linkage to and association with polycystic ovary syndrome
por: Amin, Mutaz, et al.
Publicado: (2023)

Sodium butyrate facilitates CRHR2 expression to alleviate HPA axis hyperactivity in autism-like rats induced by prenatal lipopolysaccharides through histone deacetylase inhibition
por: Wang, Xinyuan, et al.
Publicado: (2023)

miR-34b attenuates trauma-induced anxiety-like behavior by targeting CRHR1
por: Zhu, Jing, et al.
Publicado: (2017)

Degron-mediated proteolysis of CrhR-like DEAD-box RNA helicases in cyanobacteria
por: Whitman, Brendan T., et al.
Publicado: (2022)

Association analysis of polymorphisms of the CRHR1 gene with infantile spasms
por: YANG, GUANG, et al.
Publicado: (2015)

Polymorphisms in CRHR1 and the Serotonin Transporter Loci: Gene × Gene × Environment Interactions on Depressive Symptoms
por: Ressler, Kerry J, et al.
Publicado: (2010)

Lactobacillus delbrueckii alleviates depression-like behavior through inhibiting toll-like receptor 4 (TLR4) signaling in mice
por: Qiu, Xiangjie, et al.
Publicado: (2021)

BDNF-TrkB signaling-mediated upregulation of Narp is involved in the antidepressant-like effects of (2R,6R)-hydroxynorketamine in a chronic restraint stress mouse model
por: Ju, Lingsha, et al.
Publicado: (2022)

Erratum for Wang et al., “Sodium butyrate facilitates CRHR2 expression to alleviate HPA axis hyperactivity in autism-like rats induced by prenatal lipopolysaccharides through histone deacetylase inhibition”
por: Wang, Xinyuan, et al.
Publicado: (2023)

Extracellular vesicle‐mediated delivery of circDYM alleviates CUS‐induced depressive‐like behaviours
por: Yu, Xiaoyu, et al.
Publicado: (2022)

Interaction between CRHR1 and BDNF Genes Increases the Risk of Recurrent Major Depressive Disorder in Chinese Population
por: Xiao, Zheman, et al.
Publicado: (2011)

Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy
por: Li, Chunyan, et al.
Publicado: (2022)

Arbutin Alleviates LPS Induced Sepsis Pneumonia in Mice
por: Bian, Xiang-Xiang, et al.
Publicado: (2022)

ODP258 CRHR1 gene shows extensive linkage to major depression and type 2 diabetes in Italian families
por: Amin, Mutaz, et al.
Publicado: (2022)

Knockout of NPFFR2 Prevents LPS-Induced Depressive-Like Responses in Mice
por: Yu, Zachary, et al.
Publicado: (2021)

CRHR1 mediates the transcriptional expression of pituitary hormones and their receptors under hypoxia
por: Wang, Tong Ying, et al.
Publicado: (2022)

Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity
por: Flaherty, Stephen E., et al.
Publicado: (2023)

Prenatally traumatized mice reveal hippocampal methylation and expression changes of the stress-related genes Crhr1 and Fkbp5
por: Plank, Anne-Christine, et al.
Publicado: (2021)

The Effect of an α-7 Nicotinic Allosteric Modulator PNU120596 and NMDA Receptor Antagonist Memantine on Depressive-like Behavior Induced by LPS in Mice: The Involvement of Brain Microglia †
por: Alzarea, Sami, et al.
Publicado: (2022)

A Polymorphism of the Corticotropin-Releasing Hormone Receptor 2 (CRHR2) and Preterm Birth
por: Schmid, Maximilian, et al.
Publicado: (2010)

An activating mutation in the CRHR1 gene is rarely associated with pituitary-dependent hyperadrenocorticism in poodles
por: De-Marco, Viviani, et al.
Publicado: (2017)

Leukemia Inhibitory Factor Induces Proopiomelanocortin via CRH/CRHR Pathway in Mouse Trophoblast
por: Wang, He, et al.
Publicado: (2021)

Electroacupuncture Relieves LPS-Induced Depression-Like Behaviour in Rats Through IDO-Mediated Tryptophan-Degrading Pathway
por: Zhang, Kun, et al.
Publicado: (2020)

An Antagonistic Peptide of Gpr1 Ameliorates LPS-Induced Depression through the Hypothalamic-Pituitary-Ovarian Axis
por: Li, Rongrong, et al.
Publicado: (2021)

Geraniol alleviates LPS-induced acute lung injury in mice via inhibiting inflammation and apoptosis
por: Jiang, Kangfeng, et al.
Publicado: (2017)

Creatine and taurine mixtures alleviate depressive-like behaviour in Drosophila melanogaster and mice via regulating Akt and ERK/BDNF pathways
por: Kim, Suhyeon, et al.
Publicado: (2020)

The overexpression of RBM3 alleviates TBI‐induced behaviour impairment and AD‐like tauopathy in mice
por: Liu, Bingjin, et al.
Publicado: (2020)

cAMP-dependent cell differentiation triggered by activated CRHR1 in hippocampal neuronal cells
por: Inda, Carolina, et al.
Publicado: (2017)

Aneurysmal subarachnoid haemorrhage: Effect of CRHR1 genotype on mental health-related quality of life
por: Vetkas, Artur, et al.
Publicado: (2020)

Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA
por: Zalachoras, Ioannis, et al.
Publicado: (2022)

Homeostasis Imbalance of Microglia and Astrocytes Leads to Alteration in the Metabolites of the Kynurenine Pathway in LPS-Induced Depressive-Like Mice
por: Tao, Xue, et al.
Publicado: (2020)

Stattic alleviates acute hepatic damage induced by LPS/d-galactosamine in mice
por: Li, Sijia, et al.
Publicado: (2021)

Lentivirus-mediated interleukin-1β (IL-1β) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in mice
por: Li, Mengmeng, et al.
Publicado: (2017)

Mahuang-Fuzi-Xixin Decoction Reverses Depression-Like Behavior in LPS-Induced Mice by Regulating NLRP3 Inflammasome and Neurogenesis
por: Jing, Wen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7s7f80agp5aj8kcu831s2l23b5