Aspergillus Niger thermostable Cytosine deaminase-dextran conjugates with enhanced structure stability, proteolytic resistance, and Antiproliferative activity

Cytosine deaminase (CDA) is a prodrug mediating enzyme converting 5-flurocytosine into 5-flurouracil with profound broad-range anticancer activity towards various cell lines. Availability, molecular stability, and catalytic efficiency are the main limiting factors halting the clinical applications o...

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Detalles Bibliográficos
Autores principales: El-Sayed, Ashraf S. A., Rady, Amgad M., Mohamed, Hossam Taha, Zein, Nabila, Yassin, Marwa A., Mohamed, Nabil Z., Hassan, Abdallah, Amer, Mahmoud M., El-Sharakawy, Reyad, El-Sharkawy, Aya Ali, El-Sayed, Nesma, Ali, Mostafa G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830863/
https://www.ncbi.nlm.nih.gov/pubmed/36627557
http://dx.doi.org/10.1186/s12866-023-02754-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830863/
https://www.ncbi.nlm.nih.gov/pubmed/36627557
http://dx.doi.org/10.1186/s12866-023-02754-8

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