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Crosstalk between 5-methylcytosine and N(6)-methyladenosine machinery defines disease progression, therapeutic response and pharmacogenomic landscape in hepatocellular carcinoma

BACKGROUND: Accumulated evidence highlights the significance of the crosstalk between epigenetic and epitranscriptomic mechanisms, notably 5-methylcytosine (5mC) and N(6)-methyladenosine (m(6)A). Herein, we conducted a widespread analysis regarding the crosstalk between 5mC and m(6)A regulators in h...

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Detalles Bibliográficos
Autores principales: Tian, Yu, Xiao, Haijuan, Yang, Yanhui, Zhang, Pingping, Yuan, Jiahui, Zhang, Wei, Chen, Lijie, Fan, Yibao, Zhang, Jinze, Cheng, Huan, Deng, Tingwei, Yang, Lin, Wang, Weiwei, Chen, Guoyong, Wang, Peiqin, Gong, Peng, Niu, Xing, Zhang, Xianbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830866/
https://www.ncbi.nlm.nih.gov/pubmed/36627693
http://dx.doi.org/10.1186/s12943-022-01706-6