Population pharmacokinetics and limited sampling strategy for therapeutic drug monitoring of mycophenolate mofetil in Japanese patients with lupus nephritis

BACKGROUND: Mycophenolate mofetil (MMF), a prodrug of the immunosuppressive agent mycophenolic acid (MPA), is difficult to administer because of the pharmacokinetic complexity of MPA. Although dosage adjustment according to the 12-h area under the concentration–time curve (AUC(0-12)) is thought to b...

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Detalles Bibliográficos
Autores principales: Mizaki, Tomoko, Nobata, Hironobu, Banno, Shogo, Yamaguchi, Makoto, Kinashi, Hiroshi, Iwagaitsu, Shiho, Ishimoto, Takuji, Kuru, Yukiko, Ohnishi, Masafumi, Sako, Ken-ichi, Ito, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830922/
https://www.ncbi.nlm.nih.gov/pubmed/36624529
http://dx.doi.org/10.1186/s40780-022-00271-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830922/
https://www.ncbi.nlm.nih.gov/pubmed/36624529
http://dx.doi.org/10.1186/s40780-022-00271-w

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