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Binary Nanodrug-Delivery System Designed for Leukemia Therapy: Aptamer- and Transferrin-Codecorated Daunorubicin- and Luteolin-Coloaded Nanoparticles

OBJECTIVE: This study aimed to develop a binary nanodrug-delivery system decorated with aptamers (APs) and transferrin (Tf) and loaded with daunorubicin (Drn) and luteolin (Lut) for the treatment of leukemia. METHODS: Oligonucleotide AP- and Tf-contaiing ligands were designed and synthesized separat...

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Detalles Bibliográficos
Autores principales: Zhu, Yuanyuan, Zhang, Wei, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830956/
https://www.ncbi.nlm.nih.gov/pubmed/36636745
http://dx.doi.org/10.2147/DDDT.S387246