Cargando…

The gut microbiota and metabolome are associated with diminished COVID-19 vaccine-induced antibody responses in immunosuppressed inflammatory bowel disease patients

BACKGROUND: Patients with inflammatory bowel disease (IBD) treated with anti-TNF therapy exhibit attenuated humoral immune responses to vaccination against SARS-CoV-2. The gut microbiota and its functional metabolic output, which are perturbed in IBD, play an important role in shaping host immune re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alexander, James L., Mullish, Benjamin H., Danckert, Nathan P., Liu, Zhigang, Olbei, Marton L., Saifuddin, Aamir, Torkizadeh, Melissa, Ibraheim, Hajir, Blanco, Jesús Miguéns, Roberts, Lauren A., Bewshea, Claire M., Nice, Rachel, Lin, Simeng, Prabhudev, Hemanth, Sands, Caroline, Horneffer-van der Sluis, Verena, Lewis, Matthew, Sebastian, Shaji, Lees, Charlie W., Teare, Julian P., Hart, Ailsa, Goodhand, James R., Kennedy, Nicholas A., Korcsmaros, Tamas, Marchesi, Julian R., Ahmad, Tariq, Powell, Nick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831064/ https://www.ncbi.nlm.nih.gov/pubmed/36634565 http://dx.doi.org/10.1016/j.ebiom.2022.104430

Ejemplares similares

Su1611: POOR RESPONSE TO ANTI-SARS-COV-2 VACCINATION IN IMMUNOSUPPRESSED INFLAMMATORY BOWEL DISEASE PATIENTS IS ASSOCIATED WITH ALTERED GUT MICROBIOTA FUNCTION
por: Alexander, James L., et al.
Publicado: (2022)

Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on an IL23/IFNγ axis
por: Lo, Jonathan W., et al.
Publicado: (2023)

COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study
por: Alexander, James L, et al.
Publicado: (2022)

COVID-19 vaccine-induced antibody and T-cell responses in immunosuppressed patients with inflammatory bowel disease after the third vaccine dose (VIP): a multicentre, prospective, case-control study
por: Alexander, James L, et al.
Publicado: (2022)

Su1485: COVID-19 VACCINE-INDUCED ANTIBODY RESPONSES ARE IMPAIRED IN IBD PATIENTS TREATED WITH INFLIXIMAB, USTEKINUMAB OR TOFACITINIB, BUT NOT THIOPURINES OR VEDOLIZUMAB
por: Alexander, James L., et al.
Publicado: (2022)

Neutralising antibody responses against SARS-CoV-2 Omicron BA.4/5 and wild-type virus in patients with inflammatory bowel disease following three doses of COVID-19 vaccine (VIP): a prospective, multicentre, cohort study
por: Liu, Zhigang, et al.
Publicado: (2023)

Understanding anti‐TNF treatment failure: does serum triiodothyronine‐to‐thyroxine (T3/T4) ratio predict therapeutic outcome to anti‐TNF therapies in biologic‐naïve patients with active luminal Crohn's disease?
por: Lin, Simeng, et al.
Publicado: (2022)

Adalimumab and Infliximab Impair SARS-CoV-2 Antibody Responses: Results from a Therapeutic Drug Monitoring Study in 11 422 Biologic-Treated Patients
por: Chanchlani, Neil, et al.
Publicado: (2021)

Pretreatment Vitamin D Concentrations Do Not Predict Therapeutic Outcome to Anti-TNF Therapies in Biologic-Naïve Patients With Active Luminal Crohn’s Disease
por: Chanchlani, Neil, et al.
Publicado: (2023)

Meeting update: faecal microbiota transplantation––bench, bedside, courtroom?
por: Ding, Nik Sheng, et al.
Publicado: (2018)

Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study
por: Liu, Zhigang, et al.
Publicado: (2023)

Anti-TNF Biologicals Enhance the Anti-Inflammatory Properties of IgG N-Glycome in Crohn’s Disease
por: Hanić, Maja, et al.
Publicado: (2023)

Oral beclomethasone dipropionate is an effective treatment for immune checkpoint inhibitor induced colitis
por: Alexander, James L, et al.
Publicado: (2022)

Metallosis following full thickness wear in total hip arthroplasty
por: Birkett, Nicholas, et al.
Publicado: (2015)

Colorectal carcinogenesis: an archetype of gut microbiota–host interaction
por: Alexander, James L, et al.
Publicado: (2018)

Gaps in knowledge and future directions for the use of faecal microbiota transplant in the treatment of inflammatory bowel disease
por: Yalchin, Mehmet, et al.
Publicado: (2019)

Pathology of immune-mediated tissue lesions following treatment with immune checkpoint inhibitors
por: Ibraheim, Hajir, et al.
Publicado: (2019)

Rectal swabs as a viable alternative to faecal sampling for the analysis of gut microbiota functionality and composition
por: Radhakrishnan, Shiva T., et al.
Publicado: (2023)

Intestinal microbiome transfer, a novel therapeutic strategy for COVID-19 induced hyperinflammation?: In reply to, ‘COVID-19: Immunology and treatment options’, Felsenstein, Herbert McNamara et al. 2020′
por: McIlroy, James R., et al.
Publicado: (2020)

Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab
por: Lin, Simeng, et al.
Publicado: (2022)

The application of omics techniques to understand the role of the gut microbiota in inflammatory bowel disease
por: Segal, Jonathan P., et al.
Publicado: (2019)

Analysing miRNA-Target Gene Networks in Inflammatory Bowel Disease and Other Complex Diseases Using Transcriptomic Data
por: Thomas, John P., et al.
Publicado: (2022)

The implementation of omics technologies in cancer microbiome research
por: Mullish, Benjamin H, et al.
Publicado: (2018)

1171. Impact on Mortality, Length of Stay, and Antibiotic Use in Allogenic and Autologous Stem Cell Transplant Patients Colonized With Carbapenemase-Producing Enterobacteriaceae
por: Ghani, Rohma, et al.
Publicado: (2018)

The potential utility of fecal (or intestinal) microbiota transplantation in controlling infectious diseases
por: Ghani, Rohma, et al.
Publicado: (2022)

The gut microbiome: an under-recognised contributor to the COVID-19 pandemic?
por: Segal, Jonathan P., et al.
Publicado: (2020)

Sherlock: an open-source data platform to store, analyze and integrate Big Data for computational biologists
por: Bohar, Balazs, et al.
Publicado: (2023)

Short-chain fatty and carboxylic acid changes associated with fecal microbiota transplant communally influence microglial inflammation
por: Churchward, Matthew A., et al.
Publicado: (2023)

ULK1 and ULK2 are less redundant than previously thought: computational analysis uncovers distinct regulation and functions of these autophagy induction proteins
por: Demeter, Amanda, et al.
Publicado: (2020)

Mechanisms underpinning the efficacy of faecal microbiota transplantation in treating gastrointestinal disease
por: Segal, Jonathan P., et al.
Publicado: (2020)

Prednisolone has the same cardiovascular risk profile as hydrocortisone in glucocorticoid replacement
por: Smith, David J F, et al.
Publicado: (2017)

Evidence for infection in intervertebral disc degeneration: a systematic review
por: Granville Smith, Isabelle, et al.
Publicado: (2021)

SARS-CoV-2 Causes a Different Cytokine Response Compared to Other Cytokine Storm-Causing Respiratory Viruses in Severely Ill Patients
por: Olbei, Marton, et al.
Publicado: (2021)

Pathobionts in the tumour microbiota predict survival following resection for colorectal cancer
por: Alexander, James L., et al.
Publicado: (2023)

Antibiotics promote intestinal growth of carbapenem-resistant Enterobacteriaceae by enriching nutrients and depleting microbial metabolites
por: Yip, Alexander Y. G., et al.
Publicado: (2023)

Diagnostic confusion resolved by being upbeat
por: Kakar, Puneet, et al.
Publicado: (2012)

Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in humans is associated with increased signalling in the bile acid-farnesoid X receptor-fibroblast growth factor pathway
por: Monaghan, Tanya, et al.
Publicado: (2018)

Antibiotic therapy and outcome from immune-checkpoint inhibitors
por: Pinato, David J., et al.
Publicado: (2019)

Boredom in the COVID-19 Pandemic
por: Danckert, James
Publicado: (2022)

REP1 deficiency causes systemic dysfunction of lipid metabolism and oxidative stress in choroideremia
por: Cunha, Dulce Lima, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_89ug6kqf45cb29cbufpan0ps1f