Population-specific positive selection on low CR1 expression in malaria-endemic regions

Complement Receptor Type 1 (CR1) is a malaria-associated gene that encodes a transmembrane receptor of erythrocytes and is crucial for malaria parasite invasion. The expression of CR1 contributes to the rosetting of erythrocytes in the brain bloodstream, causing cerebral malaria, the most severe for...

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Detalles Bibliográficos
Autores principales: Lorenzini, Paolo Alberto, Gusareva, Elena S., Ghosh, Amit Gourav, Ramli, Nurul Adilah Binte, Preiser, Peter Rainer, Kim, Hie Lim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831336/
https://www.ncbi.nlm.nih.gov/pubmed/36626386
http://dx.doi.org/10.1371/journal.pone.0280282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831336/
https://www.ncbi.nlm.nih.gov/pubmed/36626386
http://dx.doi.org/10.1371/journal.pone.0280282

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