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Inducible lncRNA transgenic mice reveal continual role of HOTAIR in promoting breast cancer metastasis

HOTAIR is a 2.2-kb long noncoding RNA (lncRNA) whose dysregulation has been linked to oncogenesis, defects in pattern formation during early development, and irregularities during the process of epithelial-to-mesenchymal transition (EMT). However, the oncogenic transformation determined by HOTAIR in...

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Detalles Bibliográficos
Autores principales: Ma, Qing, Yang, Liuyi, Tolentino, Karen, Wang, Guiping, Zhao, Yang, Litzenburger, Ulrike M, Shi, Quanming, Zhu, Lin, Yang, Chen, Jiao, Huiyuan, Zhang, Feng, Li, Rui, Tsai, Miao-Chih, Chen, Jun-An, Lai, Ian, Zeng, Hong, Li, Lingjie, Chang, Howard Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831604/
https://www.ncbi.nlm.nih.gov/pubmed/36579891
http://dx.doi.org/10.7554/eLife.79126