Recombinant single-cycle influenza virus with exchangeable pseudotypes allows repeated immunization to augment anti-tumour immunity with immune checkpoint inhibitors

Virus-based tumour vaccines offer many advantages compared to other antigen-delivering systems. They generate concerted innate and adaptive immune response, and robust CD8(+) T cell responses. We engineered a non-replicating pseudotyped influenza virus (S-FLU) to deliver the well-known cancer testis...

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Detalles Bibliográficos
Autores principales: Kandasamy, Matheswaran, Gileadi, Uzi, Rijal, Pramila, Tan, Tiong Kit, Lee, Lian N, Chen, Jili, Prota, Gennaro, Klenerman, Paul, Townsend, Alain, Cerundolo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831609/
https://www.ncbi.nlm.nih.gov/pubmed/36626205
http://dx.doi.org/10.7554/eLife.76414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831609/
https://www.ncbi.nlm.nih.gov/pubmed/36626205
http://dx.doi.org/10.7554/eLife.76414

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