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Staphylococcus aureus adaptive evolution: Recent insights on how immune evasion, immunometabolic subversion and host genetics impact vaccine development

Despite meritorious attempts, a S. aureus vaccine that prevents infection or mitigates severity has not yet achieved efficacy endpoints in prospective, randomized clinical trials. This experience underscores the complexity of host-S. aureus interactions, which appear to be greater than many other ba...

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Detalles Bibliográficos
Autores principales: Wong Fok Lung, Tania, Chan, Liana C., Prince, Alice, Yeaman, Michael R., Archer, Nathan K., Aman, M. Javad, Proctor, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831658/
https://www.ncbi.nlm.nih.gov/pubmed/36636720
http://dx.doi.org/10.3389/fcimb.2022.1060810