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Highly sensitive liquid biopsy Duplex sequencing complements tissue biopsy to enhance detection of clinically relevant genetic variants

BACKGROUND: Liquid biopsy (LB) is a promising complement to tissue biopsy for detection of clinically relevant genetic variants in cancer and mosaic diseases. A combined workflow to enable parallel tissue and LB analysis is required to maximize diagnostic yield for patients. METHODS: We developed an...

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Detalles Bibliográficos
Autores principales: Hallermayr, Ariane, Neuhann, Teresa M., Steinke-Lange, Verena, Scharf, Florentine, Laner, Andreas, Ewald, Roland, Liesfeld, Ben, Holinski-Feder, Elke, Pickl, Julia M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831673/
https://www.ncbi.nlm.nih.gov/pubmed/36636551
http://dx.doi.org/10.3389/fonc.2022.1014592