Cargando…

Visualization of Domain- and Concentration-Dependent Impact of Thrombomodulin on Differential Regulation of Coagulation and Fibrinolysis

Background  Thrombomodulin (TM) functions as a dual modulator—anticoagulant and antifibrinolytic potential—by the thrombin-dependent activation of protein C and thrombin-activatable fibrinolysis inhibitor (TAFI). Activated TAFI cleaves the C-terminal lysine of partially degraded fibrin and inhibits...

Descripción completa

Detalles Bibliográficos
Autores principales: Mochizuki, Liina, Sano, Hideto, Honkura, Naoki, Masumoto, Kazuma, Urano, Tetsumei, Suzuki, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831690/
https://www.ncbi.nlm.nih.gov/pubmed/36307100
http://dx.doi.org/10.1055/s-0042-1757407