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Transcriptomic analysis of human ALS skeletal muscle reveals a disease-specific pattern of dysregulated circRNAs

Circular RNAs are abundant, covalently closed transcripts that arise in cells through back-splicing and display distinct expression patterns across cells and developmental stages. While their functions are largely unknown, their intrinsic stability has made them valuable biomarkers in many diseases....

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Detalles Bibliográficos
Autores principales: Tsitsipatis, Dimitrios, Mazan-Mamczarz, Krystyna, Si, Ying, Herman, Allison B., Yang, Jen-Hao, Guha, Abhishek, Piao, Yulan, Fan, Jinshui, Martindale, Jennifer L., Munk, Rachel, Yang, Xiaoling, De, Supriyo, Singh, Brijesh K., Ho, Ritchie, Gorospe, Myriam, King, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831722/
https://www.ncbi.nlm.nih.gov/pubmed/36585921
http://dx.doi.org/10.18632/aging.204450