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SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells

This study aims to explore the specific mechanisms of SALL4 on the migration, invasion and proliferation of HCC. HepG2 and SMMC-7721 cells were transfected with SALL4 NC, mimics and inhibitors. The proliferation capability and cell cycle progression of HCC cells were detected through CCK8 assay and...

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Detalles Bibliográficos
Autores principales: Tang, Zhipeng, Zhao, Pei, Zhang, Wanxing, Zhang, Qian, Zhao, Ming, Tan, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831741/
https://www.ncbi.nlm.nih.gov/pubmed/36575044
http://dx.doi.org/10.18632/aging.204446