Genetic Ablation of the DNA Damage Response Pathway Attenuates Lamin-Associated Dilated Cardiomyopathy in Mice

Hereditary dilated cardiomyopathy (DCM) is a primary disease of cardiac myocytes caused by mutations in genes encoding proteins with a diverse array of functions. Mutations in the LMNA gene, encoding the nuclear envelope protein lamin A/C, are the second most common causes of DCM. The phenotype is c...

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Detalles Bibliográficos
Autores principales: Cheedipudi, Sirisha M., Asghar, Saman, Marian, Ali J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research - Preclinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831927/
https://www.ncbi.nlm.nih.gov/pubmed/36644279
http://dx.doi.org/10.1016/j.jacbts.2022.06.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831927/
https://www.ncbi.nlm.nih.gov/pubmed/36644279
http://dx.doi.org/10.1016/j.jacbts.2022.06.015

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