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Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex

The collision sensor Hel2 specifically recognizes colliding ribosomes and ubiquitinates the ribosomal protein uS10, leading to noncanonical subunit dissociation by the ribosome-associated quality control trigger (RQT) complex. Although uS10 ubiquitination is essential for rescuing stalled ribosomes,...

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Detalles Bibliográficos
Autores principales: Matsuo, Yoshitaka, Uchihashi, Takayuki, Inada, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831982/
https://www.ncbi.nlm.nih.gov/pubmed/36627279
http://dx.doi.org/10.1038/s41467-022-35608-4