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CAR-tropic extracellular vesicles carry tumor-associated antigens and modulate CAR T cell functionality
Tumor-derived extracellular vesicles (EVs) are active contributors in metastasis and immunosuppression in tumor microenvironment. At least some of the EVs carry tumor surface molecules such as tumor-associated antigens (TAAs) and/or checkpoint inhibitors, and potentially could interact with T cells...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832131/ https://www.ncbi.nlm.nih.gov/pubmed/36627334 http://dx.doi.org/10.1038/s41598-023-27604-5 |