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Angiotensin II type 1a receptor deficiency alleviates muscle atrophy after denervation

The study aim was to determine if suppressed activation of angiotensin II type 1 receptor (AT1) prevents severe muscle atrophy after denervation. The sciatic nerves in right and left inferior limbs were cut in AT1a knockout homo (AT1a(−/−)) male mice and wild-type (AT1a(+/+)) male mice. Muscle weigh...

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Detalles Bibliográficos
Autores principales: Takayama, Suguru, Inoue, Kazuho, Ogura, Yuji, Hoshino, Seiko, Sugaya, Takeshi, Ohata, Keiichi, Kotake, Hitoshi, Ichikawa, Daisuke, Watanabe, Minoru, Kimura, Kenjiro, Shibagaki, Yugo, Kamijo-Ikemori, Atsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832142/
https://www.ncbi.nlm.nih.gov/pubmed/36627369
http://dx.doi.org/10.1038/s41598-023-27737-7