InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides

Noncanonical epitopes presented by Human Leucocyte Antigen class I (HLA-I) complexes to CD8(+) T cells attracted the spotlight in the research of novel immunotherapies against cancer, infection and autoimmunity. Proteasomes, which are the main producers of HLA-I-bound antigenic peptides, can catalyz...

Descripción completa

Detalles Bibliográficos
Autores principales: Roetschke, Hanna P., Rodriguez-Hernandez, Guillermo, Cormican, John A., Yang, Xiaoping, Lynham, Steven, Mishto, Michele, Liepe, Juliane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832164/
https://www.ncbi.nlm.nih.gov/pubmed/36627305
http://dx.doi.org/10.1038/s41597-022-01890-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832164/
https://www.ncbi.nlm.nih.gov/pubmed/36627305
http://dx.doi.org/10.1038/s41597-022-01890-6

Ejemplares similares