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InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides
Noncanonical epitopes presented by Human Leucocyte Antigen class I (HLA-I) complexes to CD8(+) T cells attracted the spotlight in the research of novel immunotherapies against cancer, infection and autoimmunity. Proteasomes, which are the main producers of HLA-I-bound antigenic peptides, can catalyz...
Autores principales: | Roetschke, Hanna P., Rodriguez-Hernandez, Guillermo, Cormican, John A., Yang, Xiaoping, Lynham, Steven, Mishto, Michele, Liepe, Juliane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832164/ https://www.ncbi.nlm.nih.gov/pubmed/36627305 http://dx.doi.org/10.1038/s41597-022-01890-6 |
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