Antiretroviral APOBEC3 cytidine deaminases alter HIV-1 provirus integration site profiles

APOBEC3 (A3) proteins are host-encoded deoxycytidine deaminases that provide an innate immune barrier to retroviral infection, notably against HIV-1. Low levels of deamination are believed to contribute to the genetic evolution of HIV-1, while intense catalytic activity of these proteins can induce...

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Detalles Bibliográficos
Autores principales: Ajoge, Hannah O., Renner, Tyler M., Bélanger, Kasandra, Greig, Matthew, Dankar, Samar, Kohio, Hinissan P., Coleman, Macon D., Ndashimye, Emmanuel, Arts, Eric J., Langlois, Marc-André, Barr, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832166/
https://www.ncbi.nlm.nih.gov/pubmed/36627271
http://dx.doi.org/10.1038/s41467-022-35379-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832166/
https://www.ncbi.nlm.nih.gov/pubmed/36627271
http://dx.doi.org/10.1038/s41467-022-35379-y

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