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P2X7 receptor activation mediates superoxide dismutase 1 (SOD1) release from murine NSC-34 motor neurons

Mutant superoxide dismutase 1 (SOD1) can be constitutively released from motor neurons and transmitted to naïve motor neurons to promote the progression of amyotrophic lateral sclerosis (ALS). However, the biological impacts of this process and the precise mechanisms of SOD1 release remain to be ful...

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Detalles Bibliográficos
Autores principales: Bartlett, Rachael, Ly, Diane, Cashman, Neil R., Sluyter, Ronald, Yerbury, Justin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832181/
https://www.ncbi.nlm.nih.gov/pubmed/35478453
http://dx.doi.org/10.1007/s11302-022-09863-5