Drugging the epigenome in the age of precision medicine

BACKGROUND: Modulating the epigenome has long been considered a potential opportunity for therapeutic intervention in numerous disease areas with several approved therapies marketed, primarily for cancer. Despite the overall promise of early approaches, however, these drugs have been plagued by poor...

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Detalles Bibliográficos
Autores principales: Feehley, Taylor, O’Donnell, Charles W., Mendlein, John, Karande, Mahesh, McCauley, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832256/
https://www.ncbi.nlm.nih.gov/pubmed/36631803
http://dx.doi.org/10.1186/s13148-022-01419-z