N-Cyano sulfilimine functional group as a nonclassical amide bond bioisostere in the design of a potent analogue to anthranilic diamide insecticide

To explore the potential of the N-cyano sulfilimine group as an amide bond isostere, a derivative of the blockbuster anthranilic diamide, chlorantramiliprole, was synthesized and evaluated with regard to its physicochemical properties, permeability, and biological activity. Given the combination of...

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Detalles Bibliográficos
Autores principales: Kang, On-Yu, Kim, Eunsil, Lee, Won Hyung, Ryu, Do Hyun, Lim, Hwan Jung, Park, Seong Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832345/
https://www.ncbi.nlm.nih.gov/pubmed/36712628
http://dx.doi.org/10.1039/d2ra06988a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832345/
https://www.ncbi.nlm.nih.gov/pubmed/36712628
http://dx.doi.org/10.1039/d2ra06988a

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