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Cytochrome P450 Transcriptional Regulation by Testis‐Specific Y‐Encoded‐Like Protein: Identification of Novel Upstream Transcription Factors

Cytochrome P450s (CYPs) display significant inter-individual variation in expression, much of which remains unexplained by known CYP single-nucleotide polymorphisms (SNPs). Testis‐specific Y‐encoded‐like proteins (TSPYLs) are transcriptional regulators for several drug-metabolizing CYPs including CY...

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Detalles Bibliográficos
Autores principales: Shivaram, Suganti, Gao, Huanyao, Qin, Sisi, Liu, Duan, Weinshilboum, Richard M., Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832376/
https://www.ncbi.nlm.nih.gov/pubmed/36153008
http://dx.doi.org/10.1124/dmd.122.000945