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Cytochrome P450 Transcriptional Regulation by Testis‐Specific Y‐Encoded‐Like Protein: Identification of Novel Upstream Transcription Factors
Cytochrome P450s (CYPs) display significant inter-individual variation in expression, much of which remains unexplained by known CYP single-nucleotide polymorphisms (SNPs). Testis‐specific Y‐encoded‐like proteins (TSPYLs) are transcriptional regulators for several drug-metabolizing CYPs including CY...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832376/ https://www.ncbi.nlm.nih.gov/pubmed/36153008 http://dx.doi.org/10.1124/dmd.122.000945 |