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Elucidating the Interactome of G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins

G protein-coupled receptors (GPCRs) are known to interact with several other classes of integral membrane proteins that modulate their biology and pharmacology. However, the extent of these interactions and the mechanisms of their effects are not well understood. For example, one class of GPCR-inter...

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Detalles Bibliográficos
Autores principales: Kotliar, Ilana B., Lorenzen, Emily, Schwenk, Jochen M., Hay, Debbie L., Sakmar, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832379/
https://www.ncbi.nlm.nih.gov/pubmed/36757898
http://dx.doi.org/10.1124/pharmrev.120.000180