Experimental and computational snapshots of C-C bond formation in a C-nucleoside synthase

The biosynthetic enzyme, ForT, catalyses the formation of a C-C bond between 4-amino-1H-pyrazoledicarboxylic acid and MgPRPP to produce a C-nucleoside precursor of formycin A. The transformation catalysed by ForT is of chemical interest because it is one of only a few examples in which C-C bond form...

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Detalles Bibliográficos
Autores principales: Li, Wenbo, Girt, Georgina C., Radadiya, Ashish, Stewart, James J. P., Richards, Nigel G. J., Naismith, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832568/
https://www.ncbi.nlm.nih.gov/pubmed/36629016
http://dx.doi.org/10.1098/rsob.220287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832568/
https://www.ncbi.nlm.nih.gov/pubmed/36629016
http://dx.doi.org/10.1098/rsob.220287

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