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M2 macrophage-derived exosomal miR-193b-3p promotes progression and glutamine uptake of pancreatic cancer by targeting TRIM62

BACKGROUND: Pancreatic cancer (PC) is a highly lethal malignancy that requires effective novel therapies. M2 macrophages are abundant in the PC microenvironment and promote cancer progression. Exosomes are emerging mediators of the crosstalk between cancer cells and the microenvironment. This study...

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Detalles Bibliográficos
Autores principales: Zhang, Ke, Li, Yu-Jie, Peng, Lin-Jia, Gao, Hui-Feng, Liu, Lu-Ming, Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832623/
https://www.ncbi.nlm.nih.gov/pubmed/36631876
http://dx.doi.org/10.1186/s13062-023-00356-y