Concept and application of the probability of pharmacological success (PoPS) as a decision tool in drug development: a position paper

BACKGROUND: In drug development, few molecules from a large pool of early candidates become successful medicines after demonstrating a favourable benefit-risk ratio. Many decisions are made along the way to continue or stop the development of a molecule. The probability of pharmacological success, o...

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Detalles Bibliográficos
Autores principales: Chen, Chao, Zhou, Xuan, Lavezzi, Silvia Maria, Arshad, Usman, Sharma, Raman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832631/
https://www.ncbi.nlm.nih.gov/pubmed/36631827
http://dx.doi.org/10.1186/s12967-022-03849-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832631/
https://www.ncbi.nlm.nih.gov/pubmed/36631827
http://dx.doi.org/10.1186/s12967-022-03849-y

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