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Concept and application of the probability of pharmacological success (PoPS) as a decision tool in drug development: a position paper
BACKGROUND: In drug development, few molecules from a large pool of early candidates become successful medicines after demonstrating a favourable benefit-risk ratio. Many decisions are made along the way to continue or stop the development of a molecule. The probability of pharmacological success, o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832631/ https://www.ncbi.nlm.nih.gov/pubmed/36631827 http://dx.doi.org/10.1186/s12967-022-03849-y |