TGF-β1 promotes SCD1 expression via the PI3K-Akt-mTOR-SREBP1 signaling pathway in lung fibroblasts

BACKGROUND: Lung fibroblast activation is associated with airway remodeling during asthma progression. Stearoyl-CoA desaturase 1 (SCD1) plays an important role in the response of fibroblasts to growth factors. This study aimed to explore the effects of SCD1 on fibroblast activation induced by transf...

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Detalles Bibliográficos
Autores principales: Zhou, Zili, Liang, Shixiu, Zhou, Zicong, Liu, Jieyi, Zhang, Jinming, Meng, Xiaojing, Zou, Fei, Zhao, Haijin, Yu, Changhui, Cai, Shaoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832654/
https://www.ncbi.nlm.nih.gov/pubmed/36627645
http://dx.doi.org/10.1186/s12931-023-02313-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832654/
https://www.ncbi.nlm.nih.gov/pubmed/36627645
http://dx.doi.org/10.1186/s12931-023-02313-9

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