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Dysfunction of the glutamatergic photoreceptor synapse in the P301S mouse model of tauopathy

Tauopathies, including Alzheimer’s disease, are characterized by retinal ganglion cell loss associated with amyloid and phosphorylated tau deposits. We investigated the functional impact of these histopathological alterations in the murine P301S model of tauopathy. Visual impairments were demonstrat...

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Detalles Bibliográficos
Autores principales: Arouche-Delaperche, L., Cadoni, S., Joffrois, C., Labernede, G., Valet, M., César, Q., Dégardin, J., Girardon, S., Gabriel, C., Krantic, S., Picaud, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832799/
https://www.ncbi.nlm.nih.gov/pubmed/36631898
http://dx.doi.org/10.1186/s40478-022-01489-3